Good science doesn't guarantee good drugs

I-20: Good Science and Good Ethics@ WhyWe Should Discourage Payment for Eggs inStem Cell Research?

Background: To evaluate current scientific and legal trends in provision of human eggs for stem cell research and to propose a policy which is both ethically and scientifically sound Materials and Methods: Literature survey of European and US policies on payment for egg donation in somatic cell nuclear transfer (SCNT) research; comparative analysis of potential for success in SCNT and induced p...

Risk assessment: good science for good decisions.

A registry including information about nearly 1,600 cases of retinoblastoma diagnosed in Britain has been created at the Childhood Cancer Research Group. Cases have been classified as 'old germ cell mutation', 'new germ cell mutation' or 'sporadic non-hereditary'. For a population-based group of 918 cases diagnosed between 1962 and 1985 we have calculated the proportions of unilateral/bilateral...

Towards Good Social Science

The rules of good science.

When scientists hear about scientific fraud, they quickly denounce the culprits as not being ‘true’ scientists. The true scientist, they argue, is only interested in unveiling step by step the countless enigmas of nature. He or she labours long hours and weekends at a desk or in the laboratory to find the truth, not to invent it. When describing her attitude to science, Nobel Prize-winning cyto...

Happy animals make good science.

In this paper the question is posed whether it is not only better for the animal to be happy, but whether its state of mind may also have the potential to influence the scientific results derived from it. To ensure good science, the animal should have a normal physiology and behaviour, apart from specific adverse effects under investigation. There is a growing body of evidence from a wide varie...