GOLD.db: genomics of lipid-associated disorders database

Genomics of platelet disorders.

Genetic diagnosis in families with inherited platelet disorders (IPD) is not performed widely because of the genetic heterogeneity of this group of disorders and because in most cases, it is not possible to select single candidate genes for analysis using clinical and laboratory phenotypes. Next-generation sequencing (NGS) technology has revolutionized the scale and cost-effectiveness of geneti...

Genomics in Neurological Disorders

Neurological disorders comprise a variety of complex diseases in the central nervous system, which can be roughly classified as neurodegenerative diseases and psychiatric disorders. The basic and translational research of neurological disorders has been hindered by the difficulty in accessing the pathological center (i.e., the brain) in live patients. The rapid advancement of sequencing and arr...

Graph Database Systems for Genomics

Genome databases have specific requirements which limit the usefulness of some database management systems. By using more appropriate database technology, a database system can be developed for genome data. We have developed a data representation based on graph theory which captures the highly interconnected structure of genome data. Graphs are a language which can be tailored for describing ge...

LIPID DISORDERS The review of medicines for treating lipid disorders

Genomics update Genomics of plant-associated microbes