منابع مشابه
The NIH ENDGAME Consortium
The effect of the 2-nitroimidazole Ro 03-8799 (8799) on the activity of 11 chemotherapeutic agents against the anaplastic MT tumour in mice has been determined by soft agar cloning. The 8799, whilst producing little cytotoxicity by itself, potentiated the cytotoxic actions of the alkylating agents melphalan and cyclophosphamide, and the nitrosoureas BCNU, CCNU and MeCCNU. This potentiation was ...
متن کاملThe Endgame in Poker
The simple two-person poker model, known as Basic Endgame, may be described as follows. With a certain probability known to both players, Player I is dealt a hand which is a sure winner. If it is not a sure winner, then Player II is sure to have a better hand. Player I may either check, in which case the better hand wins the antes, or bet. If Player I bets, Player II may either fold, conceeding...
متن کاملThe Spatial Curvature Endgame
Current constraints on spatial curvature show that it is dynamically negligible: |ΩK| . 5× 10−3 (95% CL). Neglecting it as a cosmological parameter would be premature however, as more stringent constraints on ΩK at around the 10 −4 level would offer valuable tests of eternal inflation models and probe novel large-scale structure phenomena. This precision also represents the “curvature floor”, b...
متن کاملThe Corporate Governance Endgame –
This paper examines minority squeeze-outs and their regulation in Germany, a country where majority shareholders have extensively used this tool since its introduction in 2002. Using unique data on court rulings and compensations, we analyze a sample of 324 squeeze-outs of publicly listed companies from 2002 to 2011. Large firms with foreign large shareholders are the most likely to be delisted...
متن کاملProtein folding: the endgame.
The last stage of protein folding, the "endgame," involves the ordering of amino acid side-chains into a well defined and closely packed configuration. We review a number of topics related to this process. We first describe how the observed packing in protein crystal structures is measured. Such measurements show that the protein interior is packed exceptionally tightly, more so than the protei...
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ژورنال
عنوان ژورنال: Innovation in Aging
سال: 2019
ISSN: 2399-5300
DOI: 10.1093/geroni/igz038.786