Glypican-3-Targeted Alpha Particle Therapy for Hepatocellular Carcinoma
نویسندگان
چکیده
منابع مشابه
Glypican-3 as a tumor marker for hepatocellular carcinoma
Article history: Received on: 13/03/2013 Revised on: 04/04/2013 Accepted on: 05/05/2013 Available online: 27/06/2013 Hepatocellular carcinoma(HCC) is one of the most frequent cancers in the world.The burden of HCC has been increasing in Egypt with a doubling in the incidence in the past ten years. The prognosis of most patients is unsatisfactory due to rapid clinical deterioration after the ini...
متن کاملGlypican-3 as a Serum Marker for Hepatocellular Carcinoma
To the Editor: Hippo et al. (1) have recently reported in an article published by Cancer Research that glypican-3 (GPC3) is a serologic marker of hepatocellular carcinoma (HCC). The results published by Hippo et al. basically confirm the findings reported previously by our laboratory (2) and by Nakatsura et al. (3). The fact that three independent laboratories using different anti-GPC3 antibodi...
متن کاملGlypican-3 as a Serum Marker for Hepatocellular Carcinoma
To the Editor: Hippo et al. (1) have recently reported in an article published by Cancer Research that glypican-3 (GPC3) is a serologic marker of hepatocellular carcinoma (HCC). The results published by Hippo et al. basically confirm the findings reported previously by our laboratory (2) and by Nakatsura et al. (3). The fact that three independent laboratories using different anti-GPC3 antibodi...
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Hepatocellular carcinoma (HCC) is one of the commonest cancers worldwide, as well as a common cause of cancer-related death. HCC frequently occurs in the setting of a diseased cirrhotic liver and many patients present at an advanced stage of disease. Together with a poor functional status, this often precludes the use of systemic therapy, especially conventional cytotoxic drugs. Moreover, HCC i...
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Nanocarriers, such as liposomes, have the potential to increase the payload of chemotherapeutic drugs while decreasing toxicity to non-target tissues; such advantageous properties can be further enhanced through surface conjugation of nanocarriers with targeting moieties. We previously reported that SP94 peptides, identified by phage display, exhibited higher binding affinity to human hepatocel...
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ژورنال
عنوان ژورنال: Molecules
سال: 2020
ISSN: 1420-3049
DOI: 10.3390/molecules26010004