Glycyrrhetinic acid food supplementation lowers serum potassium concentration in chronic hemodialysis patients
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Glycyrrhetinic acid food supplementation lowers serum potassium concentration in chronic hemodialysis patients.
Hyperkalemia is a common life-threatening problem in hemodialysis patients. Because glycyrrhetinic acid (GA) inhibits the enzyme 11beta-hydroxy-steroid dehydrogenase II and thereby increases cortisol availability to the colonic mineralocorticoid receptor, it has the potential to lower serum potassium concentrations. To test this, 10 patients in a 6 month prospective, double-blind, placebo-contr...
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ژورنال
عنوان ژورنال: Kidney International
سال: 2009
ISSN: 0085-2538
DOI: 10.1038/ki.2009.269