Glycoscience finally comes of age

Glycoscience finally comes of age.

Glycoscience—the study of the complex carbohydrates on the surface of proteins and lipids—has long been the neglected stepchild of molecular biology. Although genomics, proteomics and now systems biology have become hot topics of biomedical research, attracting both researchers and funding, glycoscience has played a rather minor role. Once of little interest to understanding biology on a larger...

FireWire Finally Comes Home

117 Standards I n February 1997, I wrote a Computer column titled " Linking Computers and Consumer Electronics, " which described the IEEE 1394 networking standard, otherwise known as FireWire. FireWire was designed to link personal computers, digital cameras , televisions, DVD players, printers, and other home electronics equipment. In one sense, FireWire represented the technology behind all ...

ECMO in adults for severe respiratory failure finally comes of age: just in time?

Glyceroneogenesis comes of age.

Glyceroneogenesis is a generally ignored metabolic pathway that occurs in adipose tissues and liver of mammalian species. This short review highlights a series of recent discoveries showing that glyceroneogenesis is important in lipid homeostasis.

Immunosenescence comes of age

Introduction Ageing of the immune system (immunosenescence) contributes to the increased susceptibility of the elderly to infectious disease and to the poor outcome of vaccination. Defence against pathogens is compromised mainly because of changes in adaptive immunity mediated by T and B lymphocytes; however, all components of the immune system are affected (Fig 1). Dissecting the crucial alter...