Glycosaminoglycans and Epithelial Organ Formation
نویسندگان
چکیده
منابع مشابه
Formation of a Neurosensory Organ by Epithelial Cell Slithering
Epithelial cells are normally stably anchored, maintaining their relative positions and association with the basement membrane. Developmental rearrangements occur through cell intercalation, and cells can delaminate during epithelial-mesenchymal transitions and metastasis. We mapped the formation of lung neuroepithelial bodies (NEBs), innervated clusters of neuroendocrine/neurosensory cells wit...
متن کاملExogenous glycosaminoglycans (GAG) are able to modulate avian skin differentiation (epithelial keratinization and feather formation).
Several reports have suggested that mesenchymal glycosaminoglycans (GAG) may be involved in the regulatory role of epithelial differentiation. Some researchers have pointed out that exogenous GAG affects extracellular GAG accumulation. We have therefore examined the effect of added GAG on two typical processes of avian skin differentiation: keratinization and feather formation. Glycosaminoglyca...
متن کاملLocal bradykinin formation is controlled by glycosaminoglycans.
Bradykinin is a potent inflammatory mediator that induces vasodilation, vascular leakage, and pain sensations. This short-lived peptide hormone is liberated from its large precursor protein high molecular weight kininogen (HK) through the contact system cascade involving coagulation factor XII and plasma kallikrein. Although bradykinin release is well established in vitro, the factors and mecha...
متن کاملGlycosaminoglycans in the study of mammalian organ development.
Glycosaminoglycans (GAGs) are linear polymers of amino sugar uronic acid disaccharides, and are generally attached to protein cores to form proteoglycans. GAGs interact with a large number of proteins and can participate in matrix organization, cell adhesion, differentiation, growth and apoptosis. Proteoglycans are expressed in tightly regulated spatio-temporal patterns during organ development...
متن کاملEpithelial Collagens and Glycosaminoglycans in the Embryonic Cornea
The embryonic corneal epithelium synthesizes both collagen and chondroitin sulfate and excretes them across the basement membrane into the subepithelial space where they assemble into a spiraling orthogonal matrix of fibrils. The assembly of collagen into fibrils is first apparent at the outer face of the basement membrane in a region of ordered chondroitin sulfate molecules. Hyaluronate, anoth...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: American Zoologist
سال: 1973
ISSN: 0003-1569
DOI: 10.1093/icb/13.4.1067