منابع مشابه
Glycosaminoglycans Metabolism
1Department of Surgical and Morphological Sciences, University of Insubria, via J.H. Dunant 5, 21100 Varese, Italy 2Department of Biomaterials, Radboud University Medical Center Nijmegen, 6500 HB Nijmegen, The Netherlands 3Polymer Chemistry and Biomaterials (PBM) Group, Department of Organic Chemistry, Ghent University, Krijgslaan 281 S4, 9000 Ghent, Belgium 4Gene Therapy Laboratory, Liver Unit...
متن کاملGlycosaminoglycans and Proteoglycans
In this editorial to MDPI Pharmaceuticals special issue "Glycosaminoglycans and Proteoglycans" we describe in outline the common structural features of glycosaminoglycans and the characteristics of proteoglycans, including the intracellular proteoglycan, serglycin, cell-surface proteoglycans, like syndecans and glypicans, and the extracellular matrix proteoglycans, like aggrecan, perlecan, and ...
متن کاملGlycosaminoglycans and infection.
Glycosaminoglycans (GAGs) are complex linear polysaccharides expressed in intracellular compartments, at the cell surface, and in the extracellular environment where they interact with various molecules to regulate many cellular processes implicated in health and disease. Subversion of GAGs is a pathogenic strategy shared by a wide variety of microbial pathogens, including viruses, bacteria, pa...
متن کاملGlycosaminoglycans in infectious disease.
Glycosaminoglycans (GAGs) are complex carbohydrates that are ubiquitously present on the cell surface and in the extracellular matrix. Interactions between GAGs and pathogens represent the first line of contact between pathogen and host cell and are crucial to a pathogen's invasive potential. Their complexity and structural diversity allow GAGs to control a wide array of biological interactions...
متن کاملThe Biosynthesis of Glycosaminoglycans
The sugar components of acidic glycosaminoglycans have long been known to be derived from glucose without alteration of the sugar ring (Topper & Lipton, 1953). The discovery of the nucleotide sugars by Caputto et al. (1950) and Park (1952) radically transformed the outlook on the biosynthesis of polysaccharides. It became rapidly apparent, not only that nucleotide sugars were the ‘activated’ do...
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ژورنال
عنوان ژورنال: Journal of the American Society of Nephrology
سال: 2000
ISSN: 1046-6673,1533-3450
DOI: 10.1681/asn.v112359