Glycogen Synthase Kinase 3 Gene Is Important in Growth and Molting of the Pacific White Shrimp Litopenaeus vannamei

Glycogen synthase kinase 3 (GSK3) is a vital multifunctional molecule that widely distributed in invertebrates and vertebrates. GSK3 highly conserved serine/threonine (Ser/Thr) protein kinase, which plays an important role insulin, Wnt, various signaling pathways. In this study, gene were identified the genome of Pacific white shrimp, Litopenaeus vannamei , analyzed its structure, phylogeny, expression profiles. The deduced LvGSK3 contains Ser/Thr catalytic (S_TKc) domain, exhibited high different early developmental stages, most adult tissues, premolting stages. RNA interference significantly retarded increment body weight affected expressions molting-related genes compared with control groups. These results will improve our understanding structure functions show potential applications shrimp growth.