Glycine and glycine receptor signalling in non-neuronal cells
نویسندگان
چکیده
منابع مشابه
Glycine and Glycine Receptor Signalling in Non-Neuronal Cells
Glycine is an inhibitory neurotransmitter acting mainly in the caudal part of the central nervous system. Besides this neurotransmitter function, glycine has cytoprotective and modulatory effects in different non-neuronal cell types. Modulatory effects were mainly described in immune cells, endothelial cells and macroglial cells, where glycine modulates proliferation, differentiation, migration...
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The dynamics of postsynaptic receptor scaffold formation and remodeling at inhibitory synapses remain largely unknown. Gephyrin, which is a multimeric scaffold protein, interacts with cytoskeletal elements and stabilizes glycine receptors (GlyRs) and individual subtypes of gamma-aminobutyric acid A receptors at inhibitory postsynaptic sites. We report intracellular mobility of gephyrin transpor...
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ژورنال
عنوان ژورنال: Frontiers in Molecular Neuroscience
سال: 2009
ISSN: 1662-5099
DOI: 10.3389/neuro.02.009.2009