Glyburide for the Treatment of Gestational Diabetes: A critical appraisal
نویسندگان
چکیده
منابع مشابه
Glyburide for the treatment of gestational diabetes. A critical appraisal.
The clinical experience with glyburide treatment of GDM has moved ahead of the science. A single randomized controlled trial of glyburide versus insulin indicates that glyburide treatment can provide a relatively safe alternative to insulin therapy. Subsequent retrospective trials have shown that up to 20% of GDM patients, especially those with substantial pretreatment hyperglycemia, are likely...
متن کاملPerinatal impact of the use of metformin and glyburide for the treatment of gestational diabetes mellitus.
OBJECTIVE To evaluate the perinatal impact of metformin and glyburide in the treatment of gestational diabetes mellitus (GDM). METHODS A randomized clinical trial conducted from July 2008 until September 2010 studied 200 pregnant women with GDM who required adjunctive therapy to diet and physical activity. Patients were randomized to use metformin (n=104) or glyburide (n=96). The drugs were r...
متن کاملGlyburide Versus Metformin and Their Combination for the Treatment of Gestational Diabetes Mellitus: A Randomized Controlled Study.
OBJECTIVE To compare the efficacy and safety of glyburide versus metformin and their combination for the treatment of gestational diabetes mellitus (GDM). RESEARCH DESIGN AND METHODS In this prospective randomized controlled study, we randomly assigned patients with GDM at 13-33 weeks gestation and whose blood glucose was poorly controlled by diet to receive either glyburide or metformin. If ...
متن کاملComparison of glyburide and insulin in the management of gestational diabetes: A meta-analysis
OBJECTIVE The aim of this meta-analysis was to determine the efficacy and safety of glyburide as a treatment for gestational diabetes mellitus (GDM) compared to insulin. METHODS A meta-analysis was conducted to compare the management of gestational diabetes with glyburide and insulin. Studies fulfilling all of the following inclusion criteria were included in this meta-analysis: subjects were...
متن کاملThe Development of a Critical Appraisal Tool for Use in Systematic Reviews: Addressing Questions of Prevalence
Background Recently there has been a significant increase in the number of systematic reviews addressing questions of prevalence. Key features of a systematic review include the creation of an a priori protocol, clear inclusion criteria, a structured and systematic search process, critical appraisal of studies, and a formal process of data extraction followed by methods to synthesize, or combin...
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ژورنال
عنوان ژورنال: Diabetes Care
سال: 2007
ISSN: 0149-5992,1935-5548
DOI: 10.2337/dc07-s218