Glyburide Compared to Insulin for the Treatment of Gestational Diabetes Mellitus: A Cost Analysis
نویسندگان
چکیده
منابع مشابه
Glyburide for the treatment of gestational diabetes. A critical appraisal.
The clinical experience with glyburide treatment of GDM has moved ahead of the science. A single randomized controlled trial of glyburide versus insulin indicates that glyburide treatment can provide a relatively safe alternative to insulin therapy. Subsequent retrospective trials have shown that up to 20% of GDM patients, especially those with substantial pretreatment hyperglycemia, are likely...
متن کاملPerinatal impact of the use of metformin and glyburide for the treatment of gestational diabetes mellitus.
OBJECTIVE To evaluate the perinatal impact of metformin and glyburide in the treatment of gestational diabetes mellitus (GDM). METHODS A randomized clinical trial conducted from July 2008 until September 2010 studied 200 pregnant women with GDM who required adjunctive therapy to diet and physical activity. Patients were randomized to use metformin (n=104) or glyburide (n=96). The drugs were r...
متن کاملComparison of Metformin and Insulin in treatment of Gestational Diabetes Mellitus
Introduction: Gestational Diabetes Mellitus (GDM) is one of the complications of pregnancy that has some maternal and neonatal outcomes. Some drugs such as insulin and oral agents (metformin, ...) are used for management of GDM. The aim of this study was to compare metformin and insulin in treatment of GDM Methods: This clinical trial was carried out in 2009-2011. Sample size was 201 patient...
متن کاملComparison of glyburide and insulin in the management of gestational diabetes: A meta-analysis
OBJECTIVE The aim of this meta-analysis was to determine the efficacy and safety of glyburide as a treatment for gestational diabetes mellitus (GDM) compared to insulin. METHODS A meta-analysis was conducted to compare the management of gestational diabetes with glyburide and insulin. Studies fulfilling all of the following inclusion criteria were included in this meta-analysis: subjects were...
متن کاملDiet plus insulin compared to diet alone in the treatment of gestational diabetes mellitus: a systematic review.
Fetuses of mothers with gestational diabetes mellitus are at increased risk to develop perinatal complications mainly due to macrosomia. However, in view of the marked heterogeneity of this disease, it seems difficult to set guidelines for diagnosis and treatment. This complicates the choice of assigning patients either to diet or to insulin therapy. Also of concern is how much benefit could be...
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ژورنال
عنوان ژورنال: Journal of Perinatology
سال: 2002
ISSN: 0743-8346,1476-5543
DOI: 10.1038/sj.jp.7210759