Glutathione S-transferase M1 (GSTM1) and T1 (GSTT1) variants and breast cancer risk in Burkina Faso

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Glutathione S-Transferase M1 (GSTM1) and T1 (GSTT1) Null Polymorphisms and the Risk of Hypertension: A Meta-Analysis

BACKGROUND Some studies have recently focused on the association between glutathione S-transferase M1 (GSTM1) and glutathione S-transferase T1 (GSTT1) null polymorphisms and hypertension; however, results have been inconsistent. OBJECTIVE In order to drive a more precise estimation, the present systematic review and meta-analysis is performed to investigate the relationship between the GSTM1 ...

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prevalence of null genotypes of glutathione s-transferase t1 (gstt1) and m1 (gstm1) in seven iranian populations

background: previous studies have revealed significant differences between populations for genotypic frequencies of glutathione s-transferase t1 ( gstt1 ) and m1 ( gstm1 ) polymorphisms. in order to find the frequency of the null genotypes of gstm1 and gstt1 in iranian populations, the present study was carried out. methods: the total study subjects consisted of 1340 unrelated healthy muslims/i...

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Prevalence of Null Genotypes of Glutathione S-Transferase T1 (GSTT1) and M1 (GSTM1) in Seven Iranian Populations

BACKGROUND Previous studies have revealed significant differences between populations for genotypic frequencies of glutathione S-transferase T1 (GSTT1) and M1 (GSTM1) polymorphisms. In order to find the frequency of the null genotypes of GSTM1 and GSTT1 in Iranian populations, the present study was carried out. METHODS The total study subjects consisted of 1340 unrelated healthy Muslims/Irani...

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Glutathione-S-transferase (GSTM1, GSTT1) null phenotypes and risk of lung cancer in a Korean population.

PURPOSE The aim of this study was to evaluate any association of GSTM1 and GSTT1 null genotypes with the risk of lung cancer in a South Korean population. METHODS We conducted a large-scale, population-based case-control study including 3,933 lung cancer cases and 1,699 controls. Genotypes of GSTM1 and GSTT1 were determined using real-time polymerase chain reaction. RESULTS In logistic regr...

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Glutathione S-transferases (GSTs) are encoded by a superfamily of genes and play a role in the detoxification of potential carcinogens. The human GSTs are divided into four classes: alpha, mu, pi and theta. Previous studies indicated that the absence of the Glutathione S-Transferase M1 (GSTM1) protein correlated with an increased risk of developing some types of cancers. Association between spe...

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ژورنال

عنوان ژورنال: Biomolecular Concepts

سال: 2019

ISSN: 1868-503X,1868-5021

DOI: 10.1515/bmc-2019-0020