Glutamic acid decarboxylase cDNA: nucleotide sequence encoding an enzymatically active fusion protein
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چکیده
منابع مشابه
Glutamic acid decarboxylase cDNA: nucleotide sequence encoding an enzymatically active fusion protein.
Glutamic acid decarboxylase (GAD;E.C. 4.1.1.15) catalyzes the production of GABA, the major inhibitory neurotransmitter in the mammalian brain. We recently isolated a lambda gt-11 recombinant, lambda-GAD, that contains the cDNA for GAD from feline brain (Kaufman et al., 1986). Interestingly, the beta-galactosidase-GAD fusion protein encoded by lambda GAD is enzymatically active, catalyzing the ...
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ژورنال
عنوان ژورنال: The Journal of Neuroscience
سال: 1987
ISSN: 0270-6474,1529-2401
DOI: 10.1523/jneurosci.07-09-02768.1987