Glucuronoxylan-based quince seed hydrogel: A promising scaffold for tissue engineering applications

Natural gums and mucilages from plant-derived polysaccharides are potential candidates for a tissue-engineering scaffold by their ability of gelation biocompatibility. Herein, we utilized Glucuronoxylan-based quince seed hydrogel (QSH) as tissue engineering applications. Optimization QSH was conducted varying crosslinker glutaraldehyde (GTA) concentrations. Structural characterization done Fourier Transform Infrared Spectroscopy (FTIR). Furthermore, morphological mechanical investigation performed Scanning Electron Microscopy (SEM) Atomic Force (AFM). The protein adsorption test revealed the suitability cell attachment. Biocompatibility confirmed culturing NIH-3T3 mouse fibroblast cells on it. Cell viability proliferation results that optimum parameters were 2 mg mL?1 0.03 M GTA. SEM DAPI staining indicated formation spheroids with diameter approximately 300 ?m. extracellular matrix (ECM) microenvironment Collagen Type-I staining. Here, it demonstrated fabricated is promising 3D culture applications provided its highly porous structure, remarkable swelling capacity high