منابع مشابه
PPARγ Agonist Beyond Glucose Lowering Effect
The nuclear hormone receptor PPARγ is activated by several agonists, including members of the thiazolidinedione group of insulin sensitizers. Pleiotropic beneficial effects of these agonists, independent of their blood glucose-lowering effects, have recently been demonstrated in the vasculature. PPARγ agonists have been shown to lower blood pressure in animals and humans, perhaps by suppressing...
متن کاملTolerance Does Not Develop Toward Liraglutide's Glucose-Lowering Effect.
Context Glucagon-like peptide-1 receptor agonists are popular antidiabetic drugs with potent glucose-lowering effects and low risk of hypoglycemia. Animal experiments and human data indicate that tolerance develops toward at least some of their effects (e.g., gastric motility). Whether tolerance develops toward the glucose-lowering effect of glucagon-like peptide-1 receptor agonists has never b...
متن کاملNeuronal GLP1R mediates liraglutide's anorectic but not glucose-lowering effect.
Glucose control and weight loss are cornerstones of type 2 diabetes treatment. Currently, only glucagon-like peptide-1 (GLP1) analogs are able to achieve both weight loss and glucose tolerance. Both glucose and body weight are regulated by the brain, which contains GLP1 receptors (GLP1R). Even though the brain is poised to mediate the effects of GLP1 analogs, it remains unclear whether the gluc...
متن کامل582 the Structure of Synthetic
BERGER, S.V. (1949). Acta chem. scand. 3, 660. B~RGER, S.V. (1950). Acta chem. scan& 4, 1054. ITO, T. (1950). X-ray Studies on Polymorphism. Tokyo: Maruzen. T ~ u c H I , Y. (1950). Acta Cryst. 3, 208. TXK~UCHI, Y., WATANAB~, T. & ITO, T. (1950). Acta Cryst. 3, 98. WATAN~., T. (1939). Miner. petrogr. Mitt. 50, 441. ZAC~A~IASE~, W. H. (1931). Proc. Nat. Acad. Sci. Wash. 17, 617. ZACH)~SEN, W . H...
متن کاملBlood Glucose Lowering Potential of Stem Bark of Berberis aristata Dc in Alloxan-Induced Diabetic Rats
Normal 0 false false false MicrosoftInternetExplorer4 /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0c...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: British Journal of Pharmacology
سال: 1997
ISSN: 0007-1188
DOI: 10.1038/sj.bjp.0701537