GLP-1 for type 2 diabetes

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GLP-1 for type 2 diabetes.

Glucagon-like peptide-1 (GLP-1)-based therapy of type 2 diabetes is executed either by GLP-1 receptor agonists, which stimulate the GLP-1 receptors, or by dipeptidyl peptidase-4 (DPP-4) inhibitors, which prevent the inactivation of endogenous GLP-1 thereby increasing the concentration of endogenous active GLP-1. GLP-1 activates pancreatic receptors resulting in improved glycemia through glucose...

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Purslane Effect on GLP-1 and GLP-1 receptor in type 2 diabetes

BACKGROUND The aim of this study was to examine the effect of purslane seeds in glucagon-like peptide-1 concentration and glucagon-like peptide-1 receptor in women with diabetes. METHODS This was a quasi-experimental study. The population was consisted of the city of Sari where diabetic women with diabetes II who had no history of using purslane seeds. All individuals used the same dose of me...

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The effects of twelve weeks of combined exercises on GLP-1 and insulin resistance in women with type 2 diabetes

Introdution: The purpose of this study was to investigate the effect of twelve weeks of combined exercise with two patterns (aerobic-resistance and resistance-aerobic) on GLP-1 and insulin resistance in women with type 2 diabetes. Methods: In this practical and semi-experimental study, 42 women with type 2 diabetes were divided into three groups: aerobic-resistance group (n=15), resistance-aer...

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GLP-1 Agonists in Type 1 Diabetes Mellitus.

OBJECTIVE To review the use of GLP-1 agonists in patients with type 1 diabetes mellitus (T1DM). DATA SOURCES A search using the MEDLINE database, EMBASE, and Cochrane Database was performed through March 2016 using the search terms glucagon-like peptide 1 (GLP-1) agonists, incretin, liraglutide, exenatide, albiglutide, dulaglutide, type 1 diabetes mellitus STUDY SELECTION AND DATA EXTRACTIO...

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Polymorphisms of GLP-1 Receptor Gene and Response to GLP-1 Analogue in Patients with Poorly Controlled Type 2 Diabetes

AIM The relationship between genetic polymorphisms of the glucagon-like peptide-1 (GLP-1) receptor (GLP1R) gene and unresponsiveness to GLP-1 analogue treatment in patients with poorly controlled type 2 diabetes mellitus (DM) is unclear. METHODS Thirty-six patients with poorly controlled type 2 DM were enrolled and they received six days of continuous subcutaneous insulin infusion for this st...

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ژورنال

عنوان ژورنال: Experimental Cell Research

سال: 2011

ISSN: 0014-4827

DOI: 10.1016/j.yexcr.2011.01.010