Glomerular filtration rate measurement by “single-shot” injection of inulin

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Measurement of Glomerular Filtration Rate by Rapid Intravenous Injection of a Newly Developed Inulin Fraction

OBJECTIVE Since the conventional drip-infusion method for measuring inulin clearance (Cin) has problems related to its accuracy and performance, we explored a more accurate and concise method by rapid intravenous injection of a newly developed inulin fraction (Inulead(®)), in which spot urine sampling was omitted and the administration period of inulin was shortened from 120 to 5 minutes. PAT...

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Measurement of glomerular filtration rate during flight in a migratory bird using a single bolus injection of FITC-inulin.

During migration, passerine birds typically complete a series of multi-hour flights, each followed by a period of stopover. During flight, rates of respiratory water loss are high, yet these birds show no signs of dehydration after flights. During stopover, birds become hyperphagic to replenish fat reserves, often consuming food with high water content, such as fruit. Thus migratory birds seem ...

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Measurement of glomerular filtration rate by inulin clearance without urine collection.

A continuous infusion method for measuring inulin clearance (and hence glomerular filtration rate) which does not require urine collection has been re-evaluated and found to give satisfactory results. In two non-oedematous and anephric patients the plasma level of inulin became virtually constant four hours after a single intravenous dose, and hence this is the minimum time required for the inf...

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Rapid determination of glomerular filtration rate by single-bolus inulin: a comparison of estimation analyses.

Rapid measurement of glomerular filtration rate (GFR) by an inulin single-bolus technique would be useful, but its accuracy has been questioned. We hypothesized that reported inaccuracies reflect the use of inappropriate mathematical models. GFR was measured in 14 intact and 5 unilaterally nephrectomized conscious male Sprague-Dawley rats (mean weight 368 +/- 12 g) by both single-bolus (25 mg/k...

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ژورنال

عنوان ژورنال: Kidney International

سال: 1994

ISSN: 0085-2538

DOI: 10.1038/ki.1994.267