Global trends in BRCA-related breast cancer research from 2013 to 2022: A scientometric analysis

Introduction Since the mid-2000s, breast cancer incidence among women has slowly increased at about 0.5% per year. In last three decades, Breast Cancer Susceptibility Gene ( BRCA ) been proven to be crucial gene in encouraging and development of cancer. However, scientometric analysis on -related is shortage. Thus, have a clear understanding current status catch up with hotspots, was conducted specific academic publications collected from Web Science (WoS). Methods We searched Core Collection (WoSCC) procure associated articles as our dataset. Bibliometric, CiteSpace, VOSviewer, HistCite software were then applied conduct visual analyses countries, institutions, journals, authors, landmark articles, keywords this research field. Results A total 7,266 1,310 review published between 2013 2022 retrieved eventually. The annual output steadily rose year by peaked 2021. USA led way number works, citations, collaboration. Research Treatment most favoured journal Narod SA University Toronto produced publications. At last, prominent “breast cancer” (n=1,778), “women” (n=1,369), “ brca1 ” (n=1,276), “ovarian (n=1,259), “risk” (n=1,181), “mutations” (n=929), which exposed hotspots within domain study. Conclusion tendency field over past decade presented analysis. focus clinical trials poly-adenosine diphosphate ribose polymerase inhibitors (PARPi) drugs their resistance mechanisms.