Global dynamics of a stage-structured hantavirus infection model with seasonality

In this paper, we study a time-periodic model, which incorporates seasonality and host stage-structure. This model describes the propagation of Puumala hantavirus within bank vole population Clethrionomys glareolus. The basic reproduction number R0 is obtained. By appealing to theory monotone dynamical systems chain transitive sets, establish threshold-type result on global dynamics in terms R0, that is, virus-free periodic solution globally attractive, virus dies out if ≤ 1, while there exists unique positive solution, persists > 1. Numerical simulations are given confirm our theoretical results show cleaning environment controlling grow mice essential control strategies reduce infection.