Global developmental delay with sodium valproate-induced gingival hyperplasia

The Effects of Sodium Valproate in Improving Developmental Delay in Seizure-Free Children with Abnormal Electroencephalography

Background: Developmental delay is one of the most common problems of children referred to pediatric neurology clinics. While there are reports on rehabilitation and its effects, limited studies are available to delineate pharmacotherapy of such children. Because many children with developmental delay have abnormal findings in electroencephalography, we aimed to treat a group of these children,...

Amlodipine Induced Gingival Hyperplasia

Amlodipine is a calcium channel blocker. Because of its long acting effect it is being widely used as antihypertensive drug. Gingival hyperplasia is one of its side effects. The histological and clinical evidences were consistent with amlodipine-induced gingival hyperplasia. The aim of publishing this report is to draw the attention of dentists towards this adverse effect.

Amlodipine-induced gingival hyperplasia.

Drug-induced gingival hyperplasia is a serious concern both for the patient and the clinician. A 45 year-old Caucasian male patient with hypertension, who received amlodipine (10 mg/day, single dose orally) for two months, sought medical attention because of the new-onset gingival enlargement. On clinical examination a generalized and firm overgrowth of the gingival throughout the maxilla and t...

Phenobarbital-induced Gingival Hyperplasia

Drug-Induced Gingival Hyperplasia

This article has summarized observations and results of controlled laboratory and clinical studies of drug-induced gingival hyperplasia associated with phenytoin, cyclosporine, and nifedipine use. Furthermore, information regarding the pharmacologic aspects of these medications is presented. More information is needed for a greater understanding of drug-induced gingival hyperplasia. It appears ...