Glanzmann thrombasthenia in pregnancy: Optimising maternal and fetal outcomes
نویسندگان
چکیده
منابع مشابه
Glanzmann thrombasthenia
Glanzmann thrombasthenia (GT) is a rare autosomal recessive bleeding syndrome affecting the megakaryocyte lineage and characterized by lack of platelet aggregation. The molecular basis is linked to quantitative and/or qualitative abnormalities of alphaIIb beta3 integrin. This receptor mediates the binding of adhesive proteins that attach aggregating platelets and ensure thrombus formation at si...
متن کاملGlanzmann thrombasthenia in a neonate.
Glanzmann thrombasthenia is a qualitative platelet function disorder manifested by skin bleeds, epistaxis, gingival bleeding, gastrointestinal hemorrhage, hematuria, hemarthrosis, intracranial hemorrhage and visceral hematomas. We report a six day old newborn presenting with hematuria following suprapubic aspiration, who was diagnosed as Glanzmann thrombasthenia. We believe it to be the younges...
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Neurocysticercosis (NCC) is a parasitic infection with the larvae of Taenia solium from contaminated pork. It is a leading cause of seizures in the developing world. Symptoms may be secondary to live or degenerating cysts, or previous infection causing calcification or gliosis. Diagnosis is based on clinical presentation, radiological confirmation of intracranial lesions and immunological testi...
متن کاملZinc Deficiency in Pregnancy and Fetal - Neonatal Outcomes and Impact of the Supplements on Pregnancy Outcomes
Abstract Zinc is one of the essential elements of body which has an important role in natural growth, development, and many biological performances. Zinc deficiency is a major health problem and pregnant women are at high risk. 82% of pregnant women worldwide suffer from zinc deficiency. Zinc deficiency during pregnancy has dangerous and irreparable effects such as growth impairment, spontan...
متن کاملGlanzmann Thrombasthenia: A Clinicopathological Profile.
OBJECTIVE To describe the clinical presentation of patients with Glanzmann's thrombasthenia (GT) and evaluate their diagnostic, clinical, and laboratory parameters including platelet aggregometry. STUDY DESIGN Descriptive study. PLACE AND DURATION OF STUDY Department of Hematology and Blood Transfusion, The Children Hospital and Institute of Child Health, Lahore, from January 2006 to Decemb...
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ژورنال
عنوان ژورنال: Obstetric Medicine
سال: 2016
ISSN: 1753-495X,1753-4968
DOI: 10.1177/1753495x16655021