GITR interacts with the pro-apoptotic protein Siva and induces apoptosis
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چکیده
منابع مشابه
Opium induces apoptosis in Jurkat cells via promotion of pro-apoptotic and inhibition of anti-apoptotic molecules
Objective(s): The aim of this study was to determine the important molecules involved in apoptosis induction by opium in Jurkat cell line. Materials and Methods: Jurkat cells were incubated 48 hrs with2.86×10-5 g/ml concentration of opium and apoptosis as well as expression levels of related molecules weremeasured. Results: Our results demonstrated that 50.3±0.2 percent of opium treated Jurka...
متن کاملopium induces apoptosis in jurkat cells via promotion of pro-apoptotic and inhibition of anti-apoptotic molecules
objective(s): the aim of this study was to determine the important molecules involved in apoptosis induction by opium in jurkat cell line. materials and methods: jurkat cells were incubated 48 hrs with2.86×10-5 g/ml concentration of opium and apoptosis as well as expression levels of related molecules weremeasured. results: our results demonstrated that 50.3±0.2 percent of opium treated jurkat ...
متن کاملSIVA 1 ( SIVA 1 , Apoptosis - Inducing Factor )
Review on SIVA1, with data on DNA/RNA, on the protein encoded and where the gene is implicated.
متن کاملPyrin, product of the MEFV locus, interacts with the proapoptotic protein, Siva.
Mutations in pyrin cause the autoinflammatory disorder familial Mediterranean fever (FMF), a syndrome characterized by sporadic and unpredictable attacks of fever and localized severe pain. Currently, it is not clear how attacks are triggered, nor why they spontaneously resolve after 2 or 3 days. In fact, the cellular function of the pyrin protein and the molecular underpinnings of its malfunct...
متن کاملPhosphorylation of the Pro-apoptotic Protein BIK
BIK is a pro-apoptotic BCL-2 family member and is the founding member of a subfamily of pro-apoptotic proteins known as “BH3-alone” proteins. Ectopic expression of BIK induces apoptosis in variety of mammalian cells. BIK complexes with various anti-apoptotic BCL-2 family proteins such as adenovirus E1B-19K and BCL-2 via the BH3 domain. However, the heterodimerization activity of BIK alone is in...
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ژورنال
عنوان ژورنال: Cell Death & Differentiation
سال: 2002
ISSN: 1350-9047,1476-5403
DOI: 10.1038/sj.cdd.4401140