Gillian Griffiths: How T cells get on target

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Gillian Griffiths: How T cells get on target

C ytotoxic T cells patrol body tissues in search of cells that are infected with pathogens and immediately kill any they fi nd. For the T cell, the killing process involves dramatic rearrangements of its cytoskeleton and of secre-tory granules containing cytotoxic proteins. Gillian Griffi ths blends the fi elds of immu-nology and cell biology to investigate how T cells land their killing blow. ...

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ژورنال

عنوان ژورنال: Journal of Cell Biology

سال: 2013

ISSN: 1540-8140,0021-9525

DOI: 10.1083/jcb.2001pi