Gigantic macroautophagy in programmed nuclear death ofTetrahymena thermophila

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منابع مشابه

Programmed nuclear death and its relation to apoptosis and autophagy during sexual reproduction in Tetrahymena thermophila

Department of Biology, York University, Toronto M3J 1P3, Canada Geisel School of Medicine at Dartmouth, Dartmouth College, Lebanon NH 03756, USA Graduate School of Natural Science and Technology, Kanazawa University, Kanazawa 9201192, Japan Department of Biodiversity Science, Division of Biological Resource Science, Graduate School of Agricultural Science, Tohoku University, Oosaki 989-6711, Japan

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Role of class III phosphatidylinositol 3-kinase during programmed nuclear death of Tetrahymena thermophila

Programmed nuclear death (PND) in the ciliate protozoan Tetrahymena thermophila is a novel type of autophagy that occurs during conjugation, in which only the parental somatic macronucleus is destined to die and is then eliminated from the progeny cytoplasm. Other coexisting nuclei, however, such as new micro- and macronuclei are unaffected. PND starts with condensation in the nucleus followed ...

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Role of ATG8 and autophagy in programmed nuclear degradation in Tetrahymena thermophila.

Autophagy is an evolutionarily conserved mechanism for the degradation of cellular components, but its role in enucleation during differentiation has not been established. Tetrahymena thermophila is a unicellular eukaryote with two functionally distinct nuclei, the somatic (macro-) and the germ line (micro-) nuclei. These nuclei are produced during sexual reproduction (conjugation), which invol...

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Programmed death in bacteria.

Programmed cell death (PCD) in bacteria plays an important role in developmental processes, such as lysis of the mother cell during sporulation of Bacillus subtilis and lysis of vegetative cells in fruiting body formation of Myxococcus xanthus. The signal transduction pathway leading to autolysis of the mother cell includes the terminal sporulation sigma factor Esigma(K), which induces the synt...

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Tudor nuclease genes and programmed DNA rearrangements in Tetrahymena thermophila.

Proteins containing a Tudor domain and domains homologous to staphylococcal nucleases are found in a number of eukaryotes. These "Tudor nucleases" have been found to be associated with the RNA-induced silencing complex (A. A. Caudy, R. F. Ketting, S. M. Hammond, A. M. Denli, A. M. Bathoorn, B. B. Tops, J. M. Silva, M. M. Myers, G. J. Hannon, and R. H. Plasterk, Nature 425:411-414, 2003). We hav...

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ژورنال

عنوان ژورنال: Autophagy

سال: 2010

ISSN: 1554-8627,1554-8635

DOI: 10.4161/auto.6.7.13287