Germline Genetic Risk Stratification in ALL? GATA Get More Information
نویسندگان
چکیده
منابع مشابه
GATA factor transgenes under GATA-1 locus control rescue germline GATA-1 mutant deficiencies.
GATA-1 germline mutation in mice results in embryonic lethality due to defective erythroid cell maturation, and thus other hematopoietic GATA factors do not compensate for the loss of GATA-1. To determine whether the obligate presence of GATA-1 in erythroid cells is due to its distinct biochemical properties or spatiotemporal patterning, we attempted to rescue GATA-1 mutant mice with hematopoie...
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ژورنال
عنوان ژورنال: JNCI: Journal of the National Cancer Institute
سال: 2020
ISSN: 0027-8874,1460-2105
DOI: 10.1093/jnci/djaa139