Germinal Matrix-Intraventricular Hemorrhage of the Preterm Newborn and Preclinical Models: Inflammatory Considerations
نویسندگان
چکیده
منابع مشابه
Germinal matrix hemorrhage-intraventricular hemorrhage: pathogenesis and outcomes
Germinal matrix hemorrhage-intraventricular hemorrhage (GMH-IVH) is one of the CNS injuries affecting preterm infants occurring in about 15%–20% of subjects weighing less than 1500 g. Currently, using ultrasonography, we recognize three grades of GMH-IVH. Grade I involving the subependymal parenchyma and/or extending in less than 10% of the ventricle, grade II with intraventricular bleeding not...
متن کاملCorrelation Study of Various Factors with Germinal Matrix-Intraventricular Hemorrhage in Preterm Neonates
The objective of this paper was to study various maternal and neonatal factors in relation to germinal matrix hemorrhage in preterm neonates. It was a hospital based observational study. The subjects included 120 preterm neonates with ≤34 weeks gestation with birth weight between 500 gm to 1500 gm admitted in Neonatal Intensive Care Unit of SDMH Hospital. Various maternal and neonatal risk fact...
متن کاملPreventing Germinal Matrix Layer Rupture and Intraventricular Hemorrhage
The etiology of intraventricular hemorrhage (IVH) in extremely low birth weight preterm infants is multifactorial with circulatory instability and hemostasis being preeminent. This study sought to determine if the germinal matrix layer remained intact when platelets were above 200 × 10(9)/L, a near normal level, and fell below that when IVH occurred. This was a retrospective study of platelets ...
متن کاملRisk Factors of Germinal Matrix Intraventricular Hemorrhage in Premature Infants
OBJECTIVE To determine whether some clinical parameters can be used to predict the hemorrhage and whether the relationship between these clinical variables and the grades of hemorrhage is linear. METHODS A total of 230 premature infants, born at a gestational age less than 34 weeks were retrospectively reviewed. Germinal matrix-intraventricular hemorrhage (GM-IVH), the grade of the hemorrhage...
متن کاملRisk Factors Associated with Germinal Matrix-Intraventricular Hemorrhage in Preterm Neonates
OBJECTIVE The purpose of this study is to identify the risk factors associated with the development of germinal matrix-intraventricular hemorrhage (GM-IVH) and the relationship of the severity of disease and prematurity. METHODS A total of 168 premature neonates whose birth weight ≤1500 g or gestational age ≤34 weeks were examined by cranial ultrasound (CUS) for detection of GM-IVH among the ...
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ژورنال
عنوان ژورنال: International Journal of Molecular Sciences
سال: 2020
ISSN: 1422-0067
DOI: 10.3390/ijms21218343