Germ Warfare? Strategies for Reducing the Spread of Antibiotic Resistance
نویسندگان
چکیده
منابع مشابه
Germ Warfare? Strategies for Reducing the Spread of Antibiotic Resistance
A growing body of literature describes how human pathogens in the environment acquire antibiotic resistance genes (ARGs), a process potentially boosted by selection pressure from antibiotics. Contaminated water and soil may then maintain and spread these antibiotic-resistant bacteria (ARB) and ARGs. A review in this issue of EHP examines strategies for reducing environmental pollution with anti...
متن کاملModeling the Spread of Antibiotic Resistance
This paper describes a stochastic implementation of Austin et al.’s (1999) model of the spread of antibiotic resistance in a population of fixed size under varying conditions of antibiotic use. The population is divided into sub-groups: individuals colonized by commensal bacteria and an uncolonized group. The colonized group is further divided according to whether the commensal bacteria are sen...
متن کاملGerm warfare.
Background: The major bottleneck for determination of 3 D structures of proteins using X-rays is the production of diffraction quality crystals. Often proteins are subjected to chemical modification to improve the chances of crystallization Results: Here, we report the successful crystallization of a nuclease employing a reductive methylation protocol. The key to crystallization was the success...
متن کاملAntibiotic Resistance: Origins, Evolution, Selection and Spread
Antibiotic resistance thwarts the treatment of infectious diseases worldwide. Although a number of factors can be identified which contribute to the problem, clearly the antibiotic as a selective agent and the resistance gene as the vehicle of resistance are the two most important, making up a 'drug resistance equation'. Both are needed in order for a clinical problem to arise. Given sufficient...
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ژورنال
عنوان ژورنال: Environmental Health Perspectives
سال: 2013
ISSN: 0091-6765,1552-9924
DOI: 10.1289/ehp.121-a255