منابع مشابه
Acute promyelocytic leukemia cases with nonreciprocal PML/RARa or RARa/PML fusion genes.
Tumor-associated chromosome translocations usually lead to the formation of two reciprocal fusion genes: one thought to be involved in the transformation process, the other the mechanical consequence of the translocation event. In the case of acute promyelocytic leukemia (APL) blasts, the 15;17 chromosome translocation generates the putatively transforming PML/RARa fusion gene and its reciproca...
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Because PML-RARA-induced acute promyelocytic leukemia (APL) is a morphologically differentiated leukemia, many groups have speculated about whether its leukemic cell of origin is a committed myeloid precursor (e.g. a promyelocyte) versus an hematopoietic stem/progenitor cell (HSPC). We originally targeted PML-RARA expression with CTSG regulatory elements, based on the early observation that thi...
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A 13-year-old boy presented congenital, raised, yellowish colored plaques with fi broelastic consistency, which were velvety in appearance, alopecic, with clearly defi ned limits and sulci or well-marked meandering invaginations, a cerebriform appearance on the upper part of the right ear, accompanied by alopecia in the temporomandibular region-parietal. The lesion was asymptomatic. Histopathol...
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*Centre National de la Recherche Scientifique, Unité Propre de Recherche 9051, Laboratoire associé N°11 du comité de Paris de la ligue nationale contre le cancer, conventionné par l’Université de Paris VII, Hôpital St. Louis, 75475 Paris Cedex 10, France; and §Institut de Génétique et de Biologie Moléculaire et Cellulaire, Centre National de la Recherche Scientifique-Institut National de la San...
متن کاملMolecular methods for genomic analyses of variant PML-RARA or other RARA-related chromosomal translocations in acute promyelocytic leukemia
which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. Molecular methods for genomic analyses of variant PML-RARA or other RARA-related chromo-somal translocations in acute promyelocytic leukemia TO THE EDITOR: We read an interesting paper by Palta et al. in a recent issue of the Korean Journal of Hematology tit...
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ژورنال
عنوان ژورنال: LA PALABRA
سال: 2017
ISSN: 2346-3864,0121-8530
DOI: 10.19053/01218530.n30.2017.6206