Genotypic Profile of Human Herpesvirus 8 (Kaposi's Sarcoma-Associated Herpesvirus) in Urine
نویسندگان
چکیده
منابع مشابه
Genotypic profile of human herpesvirus 8 (Kaposi's sarcoma-associated herpesvirus) in urine.
Human herpesvirus 8 (HHV-8) open reading frame K1 sequences amplified from the urine of 5 of 78 (6.4%) infected people in Malawi were monotypic. In two people, urinary and oral sequences were genotypically different. Comprehensive evaluation of HHV-8 transmission may require characterization of HHV-8 shed both in urine and orally.
متن کامل[Human herpesvirus 8/Kaposi's sarcoma-associated herpesvirus].
Human herpesvirus 8 (HHV-8), a gammaherpesvirus implicated in Kaposi's sarcoma, primary effusion lymphoma, and Castleman's disease, encodes several pathogenically important cellular homologs. To define the HHV-8 transcription program, RNA obtained from latently infected body cavity-based lymphoma 1 cells induced to undergo lytic replication was used to query a custom HHV-8 DNA microarray contai...
متن کاملKaposi’s Sarcoma and Kaposi’s Sarcoma-associated Herpesvirus/Human Herpesvirus 8: An Overview
Kaposi’s sarcoma (KS) is a vascular tumor that was brought to the attention of the medical community over a century ago in a fascinating case series in which purple-coloured nodular skin lesions were observed on five elderly men, with widespread cutaneous and visceral involvement reported in one patient at autopsy (Kaposi, 1872 as cited in Ober, 1988). This ‘Classic’ variant of KS is rare and t...
متن کاملVirology, pathogenetic mechanisms, and associated diseases of Kaposi sarcoma-associated herpesvirus (human herpesvirus 8).
Kaposi sarcoma-associated herpesvirus (KSHV) is a recently discovered and characterized member of the herpesvirus family. It is one of a few viruses proved to be associated with tumorigenesis in humans. Its causal association with 4 clinical and epidemiologic variants of Kaposi sarcoma (classic, endemic, iatrogenic, and acquired immunodeficiency virus-associated) as well as with several lymphop...
متن کاملKaposi's sarcoma-associated herpesvirus (human herpesvirus 8) infection of human fibroblast cells occurs through endocytosis.
Kaposi's sarcoma (KS)-associated herpesvirus or human herpesvirus 8 (HHV-8) DNA and transcripts have been detected in the B cells, macrophages, keratinocytes, and endothelial and epithelial cells of KS patients. In vitro, HHV-8 infects human B, endothelial, epithelial, and fibroblast cells, as well as animal cells, and the infection is characterized by (i) absence of lytic replication by the in...
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ژورنال
عنوان ژورنال: Journal of Clinical Microbiology
سال: 2004
ISSN: 0095-1137,1098-660X
DOI: 10.1128/jcm.42.7.3313-3316.2004