Genotypes Coding for Mannose-Binding Lectin Deficiency Correlated With Cryptococcal Meningitis in HIV-Uninfected Chinese Patients
نویسندگان
چکیده
منابع مشابه
Association of Fcγ Receptor IIB Polymorphism with Cryptococcal Meningitis in HIV-Uninfected Chinese Patients
BACKGROUND As important regulators of the immune system, the human Fcγ receptors (FcγRs) have been demonstrated to play important roles in the pathogenesis of various infectious diseases. The aim of the present study was to identify the association between FCGR polymorphisms and cryptococcal meningitis. METHODOLOGY/PRINCIPAL FINDINGS In this case control genetic association study, we genotype...
متن کاملmannose-binding lectin deficiency in patients with a history of recurrent infections
mannose-binding lectin (mbl) is a protein of innate immune system that is involved in opsonization and complement activation. mbl deficiency is associated with predisposition to infectious diseases; however subnormal levels are also seen in healthy subjects. the aim of this study was to investigate the prevalence and clinical manifestation of mbl deficiency in patients with increased susceptibi...
متن کاملinvestigation of mannose–binding lectin level and deficiency in patients with dermatophytosis
background dermatophytosis is a cutaneous fungal infection with a worldwide occurrence. in dermatophyte infections, the release of keratinocyte cytokines, in the presence of dermatophyte antigens, causes an acute phase response; subsequently, the acute-phase proteins are produced by hepatocytes. mannose–binding lectin (mbl), an acute-phase protein, also acts as a kind of pattern recognition rec...
متن کاملmannose-binding lectin serum levels in patients with candiduria
results in this study, 45 (13.4 %) urine samples were positive for candida species (17 males and 28 females). the most common isolated yeast was candida albicans (34%), followed by c. glabrata (32.1%), c. tropicalis (9.4%), other candida species (22.6%), and rhodotorula species (1.9%). the mean serum levels of mbl were 0.85 ± 0.01 ng/ml and 1.02 ± 0.03 ng/ml among candiduric patients and contro...
متن کاملMannose-binding lectin-deficient genotypes as a risk factor of pneumococcal meningitis in infants
OBJECTIVES The objective of this study was to evaluate to evaluate the role of mannose-binding-lectin deficient genotypes in pneumococcal meningitis (PM) in children. METHODS We performed a 16-year retrospective study (January 2001 to March 2016) including patients ≤ 18 years with PM. Variables including attack rate of pneumococcal serotype (high or low invasive capacity) and MBL2 genotypes a...
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ژورنال
عنوان ژورنال: Journal of Infectious Diseases
سال: 2011
ISSN: 0022-1899,1537-6613
DOI: 10.1093/infdis/jir152