Genome-wide methylation profiling identified novel differentially hypermethylated biomarker MPPED2 in colorectal cancer
نویسندگان
چکیده
منابع مشابه
Genome-wide profiling of DNA methylation in human cancer cells.
Global changes in DNA methylation correlate with altered gene expression and genomic instability in cancer. We have developed a methylation-specific digital sequencing (MSDS) method that can assess DNA methylation on a genomic scale. MSDS is a simple, low-cost method that combines the use of methylation-sensitive restriction enzymes with second generation sequencing technology. DNA methylation ...
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ژورنال
عنوان ژورنال: Clinical Epigenetics
سال: 2019
ISSN: 1868-7075,1868-7083
DOI: 10.1186/s13148-019-0628-y