Genome organization: Tag it, move it, place it

Cytoplasmic mRNA: move it, use it or lose it!

Once an mRNA is synthesized and processed, the immediate translation and later destruction of the transcript is not as inevitable as the central molecular biology dogma suggests. Interest in the field of post-transcriptional control continues to grow rapidly, as regulation of these multiple steps in gene expression is implicated in diverse aspects of biology such as metabolism, neurology, repro...

Photo-Based User Interfaces: Picture It, Tag It, Use It

Pervasive environments can be hard to configure and interact with using handheld computing devices, due to the mismatch between physical and digital worlds. Usually, smart resources in the user’s vicinity are discovered and presented in a menu on the user’s device from where they can be accessed. However, in environments with many embedded resources it becomes hard to identify resources by mean...

Move it or lose it: axis specification in Xenopus.

A long-standing question in developmental biology is how amphibians establish a dorsoventral axis. The prevailing view has been that cortical rotation is used to move a dorsalizing activity from the bottom of the egg towards the future dorsal side. We review recent evidence that kinesin-dependent movement of particles containing components of the Wnt intracellular pathway contributes to the for...

IT investment evaluation: why hasn't it become an organization routine?

In this study we attempt to understand why formal evaluations of IT investment projects have not yet become an organizational routine. Using survey data gathered from business and IT managers in Sweden, we tested the research hypotheses about the factors influencing the attitudes and behaviour of managers towards using formal evaluation methods based on the theory of planned behaviour. We found...

Clinical inertia: hard to move it forward.