Genome jail-break triggers lockdown

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

CCR4 drives ATLL jail break

2482 INSIGHTS | The Journal of Experimental Medicine Malaria is caused by Plasmodium parasites and is commonly thought of as a disease resulting from the cyclic infection and destruction of red blood cells. However, a subset of infected individuals will develop “cerebral malaria”—a pathogenic neuroinflammation, presumably caused by parasitized red blood cells sequestering in the brain. Those af...

متن کامل

Double strand break repair triggers genome plasticity in Streptomyces

Double strand breaks (DSB) are the most detrimental damage that bacterial cells have to cope with. Two main DSB repair pathways, namely homologous recombination (HR) and non-homologous end joining (NHEJ) are in charge of DSB repair. HR relies on an intact copy of the damaged DNA molecule as a template. On the other hand, NHEJ, which is presumably present in only 20% to 25% of the bacteria, is c...

متن کامل

Lockdown: Dynamic Control-Flow Integrity

Applications written in low-level languages without type or memory safety are especially prone to memory corruption. Attackers gain code execution capabilities through such applications despite all currently deployed defenses by exploiting memory corruption vulnerabilities. Control-Flow Integrity (CFI) is a promising defense mechanism that restricts open control-flow transfers to a static set o...

متن کامل

Simplifying Network Management with Lockdown

The administrator of an enterprise network has a responsibility to enforce the policies on the network. Yet, most security mechanisms do not map well to the intended policies. This has been due to the prevalence of simplistic tools that have poor enforcement but, yet are easy to manage. While advanced commercial solutions do exist that have stronger enforcement, they are significantly harder to...

متن کامل

Break-Induced Replication and Genome Stability

Genetic instabilities, including mutations and chromosomal rearrangements, lead to cancer and other diseases in humans and play an important role in evolution. A frequent cause of genetic instabilities is double-strand DNA breaks (DSBs), which may arise from a wide range of exogeneous and endogeneous cellular factors. Although the repair of DSBs is required, some repair pathways are dangerous b...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Nature

سال: 2017

ISSN: 0028-0836,1476-4687

DOI: 10.1038/nature24146