Genistein Content and Tyrosinase Inhibitory Activity of Edamame (Glycine max) Extracts

نویسندگان

چکیده

The study aimed to determine genistein content and tyrosinase inhibition activity of 70% ethanolic ethyl acetate extracts edamame (Glycine max) with an extraction time 15, 30, 60 minutes. Extraction was performed using the ultrasonication method. Determination carried out TLC-densitometry. Furthermore, all samples were tested for their spectrophotometric assay. Ethyl extract min exhibited highest yield (6.414% w/w), (0.169 ± 0.007% (IC50 = 72.420 0.550 µg/mL). It known that affected correlation coefficient (r) values 0.9973 0.9826, respectively. G. max suggested as a inhibitor agent from natural sources skin whitening product development due its isoflavones content, mainly genistein.

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ژورنال

عنوان ژورنال: Journal of Tropical Pharmacy and Chemistry

سال: 2022

ISSN: ['2087-7099', '2407-6090']

DOI: https://doi.org/10.25026/jtpc.v6i2.461