Genetic Variation in IL18R1 and IL18 Genes and Inteferon γ ELISPOT Response to Smallpox Vaccination: An Unexpected Relationship
نویسندگان
چکیده
منابع مشابه
Genetic variation in IL18R1 and IL18 genes and Inteferon γ ELISPOT response to smallpox vaccination: an unexpected relationship.
BACKGROUND Genetic association studies demonstrated a role for cytokine proteins and cytokine or cytokine receptor gene polymorphisms in smallpox vaccine-induced adaptive immunity. METHODS We examined the association of genetic polymorphisms with cellular (interferon [IFN] γ enzyme-linked immunospot assay [ELISPOT]) immune response to smallpox vaccine in 1076 immunized individuals. RESULTS ...
متن کاملSmallpox Vaccination
This article was presented by the author at the Vaccination Seminar of May 26, 1972, National University Medical School.
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The measurement of antibody following vaccination has been recorded in many publications. The inhibition of vaccinia haemagglutinin, because of its technical simplicity, is a method which has been commonly employed in recent years, although the complement-fixation and neutralization techniques have also been used. Some kind of neutralization test is believed to give a better measure of protecti...
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ژورنال
عنوان ژورنال: The Journal of Infectious Diseases
سال: 2013
ISSN: 1537-6613,0022-1899
DOI: 10.1093/infdis/jit341