Genetic Similarities Between Latent Autoimmune Diabetes and Type 1 and Type 2 Diabetes
نویسندگان
چکیده
منابع مشابه
Genetic similarities between latent autoimmune diabetes in adults, type 1 diabetes, and type 2 diabetes.
OBJECTIVE Latent autoimmune diabetes in adults (LADA) is often considered a slowly progressing subtype of type 1 diabetes, although the clinical picture more resembles type 2 diabetes. One way to improve classification is to study whether LADA shares genetic features with type 1 and/or type 2 diabetes. RESEARCH DESIGN AND METHODS To accomplish this, we studied whether LADA shares variation in...
متن کاملGenetic similarities between latent autoimmune diabetes and type 1 and type 2 diabetes.
In this issue of Diabetes, Cervin et al. (1) investigated whether patients with latent autoimmune diabetes in adults (LADA) (defined as age at diabetes onset 35 years, GADA positive), analyzing known risk alleles for type 1 and type 2 diabetes, share genetic polymorphisms with type 1 diabetes (age at onset 35 years) and/or type 2 diabetes (age at onset 35 years, GADA negative). In their LADA pa...
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Despite the notion that there is a degree of commonality to the biological etiology of type 1 diabetes (T1D) and type 2 diabetes (T2D), the lack of overlap in the genetic factors underpinning each of them suggests very distinct mechanisms. A disorder considered to be at the "intersection" of these two diseases is "latent autoimmune diabetes in adults" (LADA). Interestingly, genetic signals from...
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BACKGROUND LADA is probably the most prevalent form of autoimmune diabetes. Nevertheless, there are few data about cardiovascular disease in this group of patients. The aim of this study was to investigate the frequency of carotid atherosclerotic plaques in patients with LADA as compared with patients with classic type 1 diabetes and type 2 diabetes. METHODS Patients with LADA were matched fo...
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Abstract Background and objectives: Diabetes is a chronic and progressive disease resulting in disability and premature death. The Etiology of diabetes mellitus is complex, but factors such as genetic, immunological and environmental are involved .The aim of this study was to investigate the association between diabetes and blood type. Material and Methods: In this cross - sectional stu...
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ژورنال
عنوان ژورنال: Diabetes
سال: 2008
ISSN: 0012-1797,1939-327X
DOI: 10.2337/db07-1786