Genetic polymorphisms associated with rubella virus-specific cellular immunity following MMR vaccination
نویسندگان
چکیده
منابع مشابه
Characterization of rubella-specific humoral immunity following two doses of MMR vaccine using proteome microarray technology
INTRODUCTION//BACKGROUND The lack of standardization of the currently used commercial anti-rubella IgG antibody assays leads to frequent misinterpretation of results for samples with low/equivocal antibody concentration. The use of alternative approaches in rubella serology could add new information leading to a fuller understanding of rubella protective immunity and neutralizing antibody respo...
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It is possible to argue in favour of offering single vaccines even if you believe MMR to be safe, because you take the view that single vaccines are better than no vaccination at all, and/or that choice is a civil right. However, Sense believes that this is a dangerous argument. Offering single vaccines would undermine confidence in MMR, which could actually depress uptake, leading to the risk ...
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In renal transplantation, BK-virus (BKV)-associated nephropathy has emerged as a major complication, with a prevalence of 1-10% and graft loss in >50% of cases. BKV is a member of the polyomavirus family and rarely induces apparent clinical disease in the general population. However, replication of polyomaviruses, associated with significant organ disease, is observed in patients with acquired ...
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Specific cell-mediated immunity (CMI) responses to rubella virus were studied in 12 children with documented congenital rubella syndrome employing a (51)Cr lymphocytotoxicity microassay. Hemagglutination inhibition antibody was detected in 11 of the 12 children, with titers ranging from 1:4 to 1:128. CMI to rubella virus was demonstrated in only 3 of the 11 antibody-positive children. The 12th ...
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Background and Aims: Rubella is predominantly a childhood disease that is endemic throughout the world and when rubella outbreaks occur, they are accompanied by birth defects following congenital rubella syndrome. Immunity to rubella virus as a teratogenic agent has an important role for prevention of these serious congenital defects. Lymphocyte proliferation assay is a way for investigation of...
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ژورنال
عنوان ژورنال: Human Genetics
سال: 2014
ISSN: 0340-6717,1432-1203
DOI: 10.1007/s00439-014-1471-z