Genetic Mosaics and Chimeras in Mammals

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منابع مشابه

Genetic Mosaics and Chimeras in Mammals. Basic Life Sciences. Volume 12

Volume 12 of the Basic Life Sciences, Genetic Mosaics and Chimeras in Mammals, is a tremendously valuable volume; however, it suffers from several significant drawbacks. Perhaps its greatest strength is the broad range of topics considered under the general heading of chimeras and mosaics. I was especially pleased to see a section on the mathematics of the subject. The quality of the individual...

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Analysis of mouse eye development with chimeras and mosaics.

Analysis of experimental mouse chimeras (chimaeras) and mosaics provides a means of investigating patterning and differentiation within the developing mammalian eye. Chimeric and mosaic mice carry two or more genetically distinct cell populations and extend the repertoire of analytical tools available to the geneticist. Here we review the impact these techniques have had on our understanding of...

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Genetic mosaics.

Genetic mosaics can be used to gain insight into the cell specificity of gene function. How Caenorhabditis elegans mosaics are typically generated is reviewed, and several examples with relevance to developmental studies are mentioned. One example is mpk-1, which encodes a member of the Ras-MAP-kinase pathway. mpk-1 mosaics have been a means of studying the distinct cells that require the gene ...

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Interspecific chimeras in mammals: successful production of live chimeras between Mus musculus and Mus caroli.

Live chimeras between two species of mouse, Mus musculus and Mus caroli, were produced by blastocyst injection. These chimeras were entirely similar to M. musculus in equilibrium with M. musculus chimeras in their somatic tissue organization. This is the first report of completely normal development of interspecific chimeras in mammals.

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Categorization of birds, mammals, and chimeras by pigeons.

Identifying critical features that control categorization of complex polymorphous pictures by animals remains a challenging and important problem. Toward this goal, experiments were conducted to isolate the properties controlling the categorization of two pictorial categories by pigeons. Pigeons were trained in a go/no-go task to categorize black and white line drawings of birds and mammals. Th...

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ژورنال

عنوان ژورنال: Journal of Medical Genetics

سال: 1980

ISSN: 1468-6244

DOI: 10.1136/jmg.17.2.159-a