Genetic markers in clinical subtypes of juvenile idiopathic arthritis

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چکیده

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Clinical and Serological Findings in Juvenile Patients with Idiopathic Arthritis in Southwestern of Iran

Introduction: The purpose of this study was to describe clinical features and serological findings of children with idiopathic arthritis in south-western Iran.Methods: This descriptive study included 60 patients with juvenile idiopathic arthritis who were referred to a pediatric rheumatology clinic at a university hospital during 6-month period. Initial manifestations, first laboratory tests an...

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Multicentric Carpotarsal Osteolysis Mimicking Juvenile Idiopathic Arthritis

Background Multicentric carpotarsal osteolysis (MCTO), a skeletal dysplasia presents in early childhood mimicking juvenile idiopathic arthritis (JIA). Recognition of this syndrome is essential to avoid unnecessary treatment with immunosuppressive agents because of different course and treatment. Case Report A 3-year-old boy presented with swelling and restriction of right wrist joint and left ...

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Clinical outcome measures in juvenile idiopathic arthritis

Juvenile idiopathic arthritis (JIA), as a chronic condition, is associated with significant disease- and treatment-related morbidity, thus impacting children's quality of life. In order to optimize JIA management, the paediatric rheumatologist has begun to regularly use measurements of disease activity developed, validated and endorsed by international paediatric rheumatology professional socie...

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Genetic architecture distinguishes systemic juvenile idiopathic arthritis from other forms of juvenile idiopathic arthritis: clinical and therapeutic implications

OBJECTIVES Juvenile idiopathic arthritis (JIA) is a heterogeneous group of conditions unified by the presence of chronic childhood arthritis without an identifiable cause. Systemic JIA (sJIA) is a rare form of JIA characterised by systemic inflammation. sJIA is distinguished from other forms of JIA by unique clinical features and treatment responses that are similar to autoinflammatory diseases...

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MRI evaluation of clinical remission in juvenile idiopathic arthritis

Results Data of 30 patients were analysed: 26 patients in clinical remission on medication (CRM) (median duration inactive disease 0.9 years [IQ,0.6-1.2]) and 4 patients who achieved clinical remission off medication (CR) (median duration inactive disease 2.4 years [IQR,1.5-3.1]). Thirty percent of CRM patients and 1 of 4 CR patients had > 3 mm synovial thickening, suggestive for active synovit...

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ژورنال

عنوان ژورنال: Journal of Translational Medicine

سال: 2011

ISSN: 1479-5876

DOI: 10.1186/1479-5876-9-s2-p61