Genetic Determinants of Osteoporosis: Common Bases to Cardiovascular Diseases?

Genetic bases for common polygenic diseases.

The present group of articles on the genetic basis of common diseases inaugurates a new policy on the part of the editors of the Proceedings. The editors plan to present a series of written minisymposia on dynamic and emerging areas of research of interest to broad groups of readers. We will solicit and present groups of interrelated articles by leading authorities and contributors describing t...

Genetic Determinants of Heart Rate Variation and Cardiovascular Diseases

Social Determinants of Cardiovascular Diseases

Social determinants of health can be understood as the social conditions in which individuals live and work; conditions that are shaped by the distribution of power, income and resources, as much on a global and national level as on a local level. Social determinants of cardiovascular diseases are found largely outside the healthcare and preventative healthcare systems; but it is important to t...

Genetic Diseases Related with Osteoporosis

Primary osteoporosis is the disease’s most common form and results from the progressive loss of bone mass related to aging and unassociated with other illness, a natural process in adult life; its etiology is considered multifactorial and polygenic. This form currently represents a growing worldwide health problem due in part, to the contemporary environmental condi‐ tions of modern civilizatio...

Genetic and environmental determinants of osteoporosis.

Osteoporosis is a common, complex disease that is influenced by genetic and environmental factors. Although molecular genetic studies have identified several potential regions of linkage, underlying susceptibility gene(s) are largely unknown. Genetic susceptibility to osteoporosis may be both context dependent and developmentally regulated, and epigenetic mechanisms are the likely link between ...