Genetic conflicts and intercellular heterogeneity

Genetic conflicts in human pregnancy.

Pregnancy has commonly been viewed as a cooperative interaction between a mother and her fetus. The effects of natural selection on genes expressed in fetuses, however, may be opposed by the effects of natural selection on genes expressed in mothers. In this sense, a genetic conflict can be said to exist between maternal and fetal genes. Fetal genes will be selected to increase the transfer of ...

Genetic conflicts: the usual suspects and beyond.

Selfishness is pervasive and manifests at all scales of biology, from societies, to individuals, to genetic elements within a genome. The relentless struggle to seek evolutionary advantages drives perpetual cycles of adaptation and counter-adaptation, commonly referred to as Red Queen interactions. In this review, we explore insights gleaned from molecular and genetic studies of such genetic co...

Genetic heterogeneity of cebocephaly.

Gap junction mediated miRNA intercellular transfer and gene regulation: A novel mechanism for intercellular genetic communication.

Intercellular genetic communication is an essential requirement for coordination of cell proliferation and differentiation and has an important role in many cellular processes. Gap junction channels possess large pore allowing passage of ions and small molecules between cells. MicroRNAs (miRNAs) are small regulatory RNAs that can regulate gene expression broadly. Here, we report that miRNAs can...

Possible conflicts, ARRs, and conflicts

Consistency-based diagnosis is the most widely used approach to model-based diagnosis within the Artificial Intelligence community. It is usually carried out through an iterative cycle of behavior prediction, conflict detection, and candidate generation and refinement. Many approaches to consistency-based diagnosis have relied on some kind of on-line dependency-recording mechanism for conflict ...