Genetic-clinical profile of subjects with apparently sporadic extra-adrenal paragangliomas
نویسندگان
چکیده
منابع مشابه
Genetic-Clinical Profile of Subjects with Apparently Sporadic Extra-Adrenal Paragangliomas
BACKGROUND Mutations in the genes encoding B, C, and D subunits of the succinate dehydrogenase (SDH) are involved in the pathogenesis of familial paraganglioma (PGL) syndrome. Many subjects with apparently sporadic extra-adrenal paragangliomas are found to be carrier for SDH mutation. OBJECTIVE Here we describe four subjects with apparently sporadic extra-adrenal paragangliomas with newly ide...
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AIM To examine whether adrenal phaeochromocytomas and extra-adrenal paragangliomas are immunoreactive for commercially available and routinely used cytokeratin antibodies. METHODS 18 extra-adrenal paragangliomas and seven adrenal phaeochromocytomas were stained with CAM 5.2, AE1/3, and 34 beta E12 following microwave antigen retrieval of formalin fixed tissue. RESULTS A single case from the...
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ژورنال
عنوان ژورنال: Frontiers in Endocrinology
سال: 2012
ISSN: 1664-2392
DOI: 10.3389/fendo.2012.00065