Genetic aspects of immunologic abnormalities in New Zealand mouse strains
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New Zealand obese (NZO/HlLt) male mice develop polygenic diabetes and altered phosphatidylcholine metabolism. The gene encoding phosphatidylcholine transfer protein (PC-TP) is sited within the support interval for Nidd3, a recessive NZO-derived locus on Chromosome 11 identified by prior segregation analysis between NZO/HlLt and NON/Lt. Sequence analysis revealed that the NZO-derived PC-TP conta...
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ژورنال
عنوان ژورنال: Arthritis & Rheumatism
سال: 1978
ISSN: 0004-3591,1529-0131
DOI: 10.1002/art.1780210916