Genesis of Monkeypox

Monkeypox virus.

INTRODUCTION ......... ..................................... I HISTORICAL NOTE ........... ................................... 2 Recognition of Monkeypox in Nonhuman Primates ....... ..................... 2 Human Infection with Monkeypox Virus ..................................... 3 CLASSIFICATION .......... .................................... 3 MONKEYPOX VIRUS AS AN INFECTIOUS AGENT ...... .....

Retrospective Analysis of Monkeypox Infection

Serologic cross-reactivity between orthopoxviruses is a substantial barrier to laboratory diagnosis of specific orthopoxvirus infections and epidemiologic characterization of disease outbreaks. Historically, time-consuming and labor-intensive strategies such as cross-adsorbed neutralization assays, immunofluorescence assays, and hemagglutination-inhibition assays have been used to identify orth...

A Phylogeographic Investigation of African Monkeypox

Monkeypox is a zoonotic disease caused by a virus member of the genus Orthopoxvirus and is endemic to Central and Western African countries. Previous work has identified two geographically disjuct clades of monkeypox virus based on the analysis of a few genomes coupled with epidemiological and clinical analyses; however, environmental and geographic causes of this differentiation have not been ...

Monkeypox outbreak among pet owners.

A tale of two clades: monkeypox viruses.

Human monkeypox was first recognized outside Africa in 2003 during an outbreak in the USA that was traced to imported monkeypox virus (MPXV)-infected West African rodents. Unlike the smallpox-like disease described in the Democratic Republic of the Congo (DRC; a Congo Basin country), disease in the USA appeared milder. Here, analyses compared clinical, laboratory and epidemiological features of...