Genes encoding acyl-CoA dehydrogenase (AcdH) homologues from Streptomyces coelicolor and Streptomyces avermitilis provide insights into the metabolism of small branched-chain fatty acids and macrolide antibiotic production The GenBank accession numbers for the sequences described in this paper are AF142581 (Streptomyces coelicolor) and AF143210 (Streptomyces avermitilis).
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Repression in Streptomyces coelicolor
A glucose kinase (glkA) mutant of Streptomyces coelicolor A3(2) M145 was selected by the ability to grow in the presence of the nonmetabolizable glucose analog 2-deoxyglucose. In this glk4 mutant, carbon catabolite repression of glycerol kinase and agarase was relieved on several carbon sources tested, even though most of these carbon sources are not metabolized via glucose kinase. This suggest...
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In bacteria, small RNAs (sRNAs) make important regulatory contributions to an ever increasing number of cellular processes. To expand the repertoire of known sRNAs, we sought to identify novel sRNAs in the differentiating, multicellular bacterium Streptomyces coelicolor. We describe a combined bioinformatic and experimental approach that enabled the identification and characterization of nine n...
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This thesis cannot be reproduced or quoted extensively from without first obtaining permission in writing from the Author The content must not be changed in any way or sold commercially in any format or medium without the formal permission of the Author When referring to this work, full bibliographic details including the author, title, awarding institution and date of the thesis must be given ...
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interaction of two complementary growth-factor dependent mutants, i.e., Tzp lemen ta ry auxotrophs, of Streptomyces coeticolor to form grovvth-factor independent progeny, i.e., prototrophs, was interpreted as gene recombination by SERMO~TI and SPADA-SERMONTI (1955) and by BRAENDLE and SZ+BALSKI (1959yi but as heterokaryosis by BRADLEY (1957). The former workers concluded that gene recombination...
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ژورنال
عنوان ژورنال: Microbiology
سال: 1999
ISSN: 1350-0872,1465-2080
DOI: 10.1099/00221287-145-9-2323