منابع مشابه
Oxycodone Controlled Release in Cancer Pain Management
Oral opioids are the treatment of choice for chronic cancer pain. Morphine is the strong opioid of choice for the treatment of moderate to severe cancer pain according to guidelines from the World Health Organization (WHO). This recommendation by the WHO was derived from availability, familiarity to clinicians, established effectiveness, simplicity of administration, and relative inexpensive co...
متن کاملControlled-release oxycodone for neuropathic pain and fibromyalgia in adults.
Practice Pointers Chronic neuropathic pain and fibromyalgia are estimated to affect 10% of adults older than 30 years.1 Neuropathic pain is classically difficult to treat, requiring a multidisciplinary approach with pharmacologic, physical, and mental health interventions. Even with a multifaceted approach, few patients achieve appreciable pain relief (i.e., at least a 50% reduction in pain int...
متن کاملEfficacy and safety of controlled-release oxycodone/naloxone versus controlled-release oxycodone in Korean patients with cancer-related pain: a randomized controlled trial
BACKGROUND Controlled-release oxycodone/naloxone (OXN-CR) maintains the effect of opioid-induced analgesia through oxycodone while reducing the occurrence rate of opioid-induced constipation through naloxone. The present study was designed to assess the non-inferiority of OXN-CR to controlled-release oxycodone (OX-CR) for the control of cancer-related pain in Korean patients. METHODS In this ...
متن کاملControlled-release oxycodone relieves neuropathic pain: a randomized controlled trial in painful diabetic neuropathy.
BACKGROUND Painful neuropathy is one of the most common long-term complications of diabetes mellitus and often proves difficult to relieve. METHODS Patients with diabetic neuropathy with moderate or greater pain for at least 3 months, were evaluated for efficacy, safety and health-related quality of life (QOL) while receiving controlled-release (CR) oxycodone (OxyContin) or active placebo. Pa...
متن کاملControlled-release oxycodone for pain in diabetic neuropathy: a randomized controlled trial.
BACKGROUND AND OBJECTIVE Opioid treatment has played a limited role in the management of diabetic neuropathy, in part because of concerns about the responsiveness of neuropathic pain to opioid treatment. This controlled study evaluated the efficacy and safety of controlled-release (CR) oxycodone in subjects with moderate to severe pain due to diabetic neuropathy. METHODS This multicenter, ran...
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ژورنال
عنوان ژورنال: Canadian Medical Association Journal
سال: 2013
ISSN: 0820-3946,1488-2329
DOI: 10.1503/cmaj.113-2134