General Principles for the Detection of Modified Nucleotides in RNA by Specific Reagents (Adv. Biology 10/2021)
نویسندگان
چکیده
Graphene Based Materials In article 2100866, Helm and co-workers review that RNA nucleobases are known to feature intrinsic reactivity towards a number of chemical reagents from organic chemistry but also occurring in our environment. Some allow discriminate canonical modifications.
منابع مشابه
Use of Specific Chemical Reagents for Detection of Modified Nucleotides in RNA
Naturally occurring cellular RNAs contain an impressive number of chemically distinct modified residues which appear posttranscriptionally, as a result of specific action of the corresponding RNA modification enzymes. Over 100 different chemical modifications have been identified and characterized up to now. Identification of the chemical nature and exact position of these modifications is typi...
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ژورنال
عنوان ژورنال: Advanced biology
سال: 2021
ISSN: ['2701-0198']
DOI: https://doi.org/10.1002/adbi.202170101