Gene Unscrambler for detangling scrambled genes in ciliates
نویسندگان
چکیده
منابع مشابه
Two Models for Gene Assembly in Ciliates
Two models for gene assembly in ciliates have been proposed and investigated in the last few years. The DNA manipulations postulated in the two models are very different: one model is intramolecular – a single DNA molecule is involved here, folding on itself according to various patterns, while the other is intermolecular – two DNA molecules may be involved here, hybridizing with each other. Co...
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Determination of the number of times that plastids have been gained and lost during eukaryotic evolution has proven difficult. A recent study has uncovered what could be the molecular signature of a photosynthetic ancestry for an important plastid-lacking lineage of microbial eukaryotes--the ciliates.
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UNLABELLED Chromosome rearrangements occur in a variety of eukaryotic life cycles, including during the development of the somatic macronuclear genome in ciliates. Previous work on the phyllopharyngean ciliate Chilodonella uncinata revealed that macronuclear β-tubulin and protein kinase gene families share alternatively processed germ line segments nested within divergent regions. To study geno...
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Ciliates are highly complex single-cell organisms, yet very successful from evolutionary point of view they emerged eon years ago and derived into many thousands of known species. Robustness may have an essential contribution to their survival. In this paper, we discuss the robustness of ciliates gene assembly, a process that transforms a diploid micronucleus to a macronucleus and involves mass...
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reduction graphs be ARG. It turns out that there are graphs in ARG that are not (isomorphic to) reduction graphs. To obtain a characterization we need one more property of reduction graphs: the ability to linearly order the vertices to resemble its (in general not unique) underlying legal string, as done in Fig. 11. To make this linear order of vertices explicit, we introduce a third set of edg...
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ژورنال
عنوان ژورنال: Bioinformatics
سال: 2004
ISSN: 1367-4803,1460-2059
DOI: 10.1093/bioinformatics/bth003