Gene-environment interactions between GSTs polymorphisms and targeted epigenetic alterations in hepatocellular carcinoma following organochlorine pesticides (OCPs) exposure
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چکیده
منابع مشابه
Organochlorine pesticides exposure & preterm birth
occurs before 37 wk gestational age. In USA, the preterm delivery rate is 12-13 per cent; in Europe and other developed countries, reported rates are generally 5-9 per cent 1. PTB accounts for 75 per cent of perinatal mortality and it is the leading direct cause of prenatal and neonatal death, resulting in 3.1 million newborn deaths annually. Half of preterm infants have longterm morbidity such...
متن کاملConcentrations of organochlorine pesticides (OCPs) in human blood plasma from Hong Kong: markers of exposure and sources from fish.
Previous studies revealed that food, particularly fish products, is the major source for human exposure to organochlorine pesticides (OCPs). Our previous studies revealed that contamination of Hong Kong market fish with DDT was 0.74-131 with a mean of 12.2 ng g(-1), ww, a result suggested that local people might be exposed to hazardous concentrations of OCPs. Therefore, the present systematic s...
متن کاملThe levels and distribution of organochlorine pesticides (OCPs) in sediments from the Haihe River, China.
The levels and distribution patterns of the selected organochlorine pesticides (OCPs=p,p'-DDT, o,p'-DDT, p,p'-DDE, p,p'-DDD, alpha-, beta-, gamma- and delta-HCH) in surficial sediments from the Haihe River and Dagu Drainage River of Tianjin were investigated by means of gas chromatography coupled with micro-electronic capture detector (GC-microECD). Concentrations of OCPs in the sediments from ...
متن کاملDistribution of organochlorine pesticides (OCPs) in conifer needles in the southeast Tibetan Plateau.
Twenty-nine conifer needles in mountain-valley areas from the southeastern Tibet were collected with altitude span from 1520 to 4340m above sea level (m.a.s.l.). They were analyzed for organochlorine pesticides (OCPs), including hexachlorocyclohexanes (alpha-, beta-, gamma- and delta-HCH), dichlorodiphenyltrichloroethane (p,p'-DDE, p,p'-DDD, o,p'-DDT and p,p'-DDT) and hexachlorobenzene (HCB). C...
متن کاملCYP polymorphisms and pathological conditions related to chronic exposure to organochlorine pesticides
The association between genetic variations in the cytochrome P450 (CYP) family genes and pathological conditions related to long-term exposure to organochlorine compounds (OCs) deserves further elucidation. OCs are persistent organic pollutants with bioaccumulative and lipophilic characteristics. They can act as endocrine disruptors and perturb cellular mechanisms. Prolonged exposure to OCs has...
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ژورنال
عنوان ژورنال: Environment International
سال: 2020
ISSN: 0160-4120
DOI: 10.1016/j.envint.2019.105313